Published IRF-Supported Research

  1. Bell, S.J. and Sears, B. "Low-glycemic load diets: Impact on obesity and chronic diseases." Crit Rev Food Sci and Nutr 43: 357-377 (2003)
  2. Bell SJ and Sears B. "A proposal for a new national diet: a low glycemic-load diet with a Unique Macro-nutrient Composition." Metabol Synd and Related Disord 1:199-208 (2003)
  3. Bell SJ and Sears B. "The Zone diet: an anti-inflammatory, low glycemic-load diet." Metabol Synd and Related Disord 2:24-38 (2004)
  4. Johnston CS, Tjonn SL, Swan PD, White A, and Sears B. "Low-carbohydrate, high-protein diets that restrict potassium-rich fruits and vegetables promote calciuria." Osteoporos Int 17: 1820-1821 (2006)
  5. Johnston, CS, White AM, Tjonn, S, Swan PD, Hutchins H, and Sears B. "Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate diets. Reply to NJ Krilanovich." Am J Clin Nutr 85: 239 (2007)
  6. Sorgi PJ, Hallowell EM, Hutchins HL, and Sears B. "Effects of an open-label pilot study with high-dose EPA/DHA concentrates on plasma phospholipids and behavior in children with attention deficit hyperactivity disorder" Nutr J 13:16 (2007)
  7. White AM, Johnston CS, Swan PD, Tjonn SL, and Sears B. "Blood ketones are directly related to fatigue and perceived effort during exercise in overweight adults adhering to low-carbohydrate diets for weight loss: A pilot study." J Am Diet Assoc 107: 1792-1796 (2007)
  8. Sears B. "Anti-inflammatory diets for obesity and diabetes." J Coll Amer Nutr 28: 482S-491S (2009)
  9. Mills JD, Bailes JE, Sedney CL, Hutchins H, and Sears B. "Omega-3 dietary supplementation reduces traumatic axonal injury in a rodent head injury model" J Neurosurgery 114: 77-84 (2011)
  10. Sears B and Ricordi C. "Anti-inflammatory nutrition as a pharmacological approach to treat obesity." J Obesity 2011: 431985 (2011)
  11. Sears B and Ricordi C. "Role of fatty acids and polyphenols in inflammatory gene transcription and their impact on obesity, metabolic syndrome, and diabetes." Eur Rev Med Pharmacol Sci 16: 1137-1154 (2012)
  12. Lotrich, FE, Sears, B, and McNamara RK. "Elevated ratio of arachidonic acid to long-chain omega-3 fatty acids predicts depression development following interferon- alpha treatment: Relationship with interleukin-6." Brain, Behavior, and Immunity 31: 48-53 (2013)
  13. Sears B, Bailes J, and Asselin B. "Therapeutic uses of high-dose omega-3 fatty acids to treat comatose patients with severe brain injury." PharmaNutrition 1: 86-89 (2013)
  14. Lotrich FE, Sears B, and McNamara R.K. "Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids." J Psychosomatic Res 75:475-483 (2013)
  15. McNamara RK, Perry M, and Sears, B. "Dissociation of C-reactive protein levels from long-chain omega-3 fatty acid status and anti-depressant response in adolescents with major depressive disorder: an open-label dose-ranging trial." J Nutr Therapeutics 2:235-243 (2013)
  16. Georgiou T, Neokleous A, Nikolaou D, and Sears B. "Pilot study for treating dry age-related macular degeneration (AMD) with high-dose omega-3 fatty acids." PharmaNutrition 2:8-11 (2014)
  17. Sears B and Perry M. "The role of fatty acids in insulin resistance." Lipids Health Disease 14:121 (2015)
  18. Sears B. "Anti-inflammatory diets.”" J Am Coll Nutr 34: Suppl 1 14-21 (2015)
  19. Lotrich FE, Sears B, and McNamara RK. "Polyunsaturated fatty acids moderate the effect of poor sleep on depression risk." Prostaglandins Leukot Essent Fatty Acids 106:19-25 (2016)
  20. Sears B. "High-dose omega-3 fatty acids and vitamin D for preservation of residual beta cell mass in type 1 diabetes." CellR4 4:e2107 (2016)
  21. Sears B. "Delaying adverse health consequences of aging: The role of omega-3 fatty acids on inflammation and resoleomics." CellR4 4:e2111 (2016)
  22. Sears B. "Omega-3 fatty acids and cardiovascular disease: Do placebo doses give placebo results?" CellR4 5:e2302 (2017)
  23. Sears B. "Polyphenols: Novel applications in human health." CellR4 5:e2437 (2017)
  24. Johnson CS, Sears B, Perry M, and Knurick JR. "Use of novel high-protein functional food products as part of a calorie-restricted diet to reduce insulin resistance and increase lean body mass in adults: A randomized controlled trial." Nutrients 9:1182 (2017)
  25. Davinelli S, Corbi G, Righetti S, Sears B, Olarte HH, Grassi D, and Scapagnini G. ""Cardioprotection by cocoa polyphenols and omega-3 fatty acids: A disease-prevention perspective on aging-associated cardiovascular risk." J Med Food 21:1-10 (2018)
  26. Sears B. "Omega-3 fatty acids and cardiovascular disease: Dose and AA/EPA ratio determine the therapeutic outcome." CellR4 6:e253 l (2018)
  27. Infante M, Sears B, Rizzo AM, Mariani Cerati D, Caprio M, Ricordi C, and Fabbri A. "Omega-3 PUF As and vitamin D co-supplementation as a safe-effective therapeutic approach for core symptoms of autism spectrum disorder: case report and literature review." Nutr Neurosci 13:1-12 (2018)
  28. Sears B. "Appropriate doses of omega-3 fatty acids for therapeutic results." CellR4 6: e2578 (2018)
  29. Infante, M, Ricordi C, Baidal DA, Alejandro R, Lonzoni G, Sears B, Caprio M, and Fabbri A. "VITAL study: An incomplete picture?" Eur Rev Med Phann Sci 23: 3142- 3147 (2019)
  30. NaPier Z, Kanim LEA, Arabi Y, Salehi K, Sears B, Perry M, Kim S, Sheyn D, Bae HW, and Glaeser JD. "Omega-3 fatty acid supplementation reduces intervertebral disc degeneration." Med Sci Monit 14 :9531-9537 (2019)